Stanozolol CIII (200 mg) - Names and Identifiers
Name | Stanozolol
|
Synonyms | Stanzolol Stanazolol Stanozolol Winstrol l ndrostanazol Stanozolol CIII (200 mg) Stanozolol(Winstrol, Winstrol Depot) Stanozolol Suspension (For Injection) 17beta-Hydroxy-17-methyl-5alpha-androstano[3,2-c]pyrazole 2-c)pyrazol-17beta-ol,17-methyl-2'h-5alpha-androst-2-eno( 17-alpha-methyl-5-alpha-androstano(3,2-c)pyrazol-17-beta-ol 2'H-5alpha-Androst-2-eno(3,2-c)pyrazol-17beta-ol, 17-methyl- 2-c)pyrazol-17-ol,17-methyl-,(5alpha,17beta)-2'h-androst-2-eno( 2'H-Androst-2-eno[3,2-c]pyrazol-17-ol, 17-methyl-, (5alpha,17beta)- 1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol (1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol
|
CAS | 10418-03-8
|
EINECS | 233-894-8 |
InChI | InChI=1/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1 |
InChIKey | LKAJKIOFIWVMDJ-IYRCEVNGSA-N |
Stanozolol CIII (200 mg) - Physico-chemical Properties
Molecular Formula | C21H32N2O
|
Molar Mass | 328.49 |
Density | 1.129±0.06 g/cm3(Predicted) |
Melting Point | 242 °C |
Boling Point | 490.8±45.0 °C(Predicted) |
Specific Rotation(α) | 34 º |
Flash Point | -2℃ |
Solubility | Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethanol (96 per cent), very slightly soluble in methylene chloride. |
Vapor Presure | 1.89E-10mmHg at 25°C |
Appearance | powder |
Color | white to light yellow |
Merck | 8794 |
pKa | 15.15±0.60(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 34 ° (C=0.4, CHCl3) |
Physical and Chemical Properties | Specific optical rotation: 34 ° |
Use | For chronic wasting disease, serious illness and postoperative weakness emaciation, frail elderly, osteoporosis, children with dysplasia, aplastic anemia, etc |
Stanozolol CIII (200 mg) - Risk and Safety
Risk Codes | R63 - Possible risk of harm to the unborn child
R38 - Irritating to the skin
R19 - May form explosive peroxides
R11 - Highly Flammable
R61 - May cause harm to the unborn child
R60 - May impair fertility
|
Safety Description | S53 - Avoid exposure - obtain special instructions before use.
S22 - Do not breathe dust.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN2252 - class 3 - PG 2 - 1,2-Dimethoxyethane solution |
WGK Germany | 3 |
RTECS | BV8741000 |
HS Code | 29372900 |
Stanozolol CIII (200 mg) - Standard
Authoritative Data Verified Data
This product is 17-methyl -2 'H-5a-androsten-2-ene-[3,2-c] pyrazol-17b-ol. Calculated as dried product, the content of C21H32N20 shall not be less than 98.0%.
Last Update:2024-01-02 23:10:35
Stanozolol CIII (200 mg) - Trait
Authoritative Data Verified Data
- This product is white crystalline powder; Odorless; Slightly hygroscopic.
- This product is slightly soluble in ethanol or chloroform, slightly soluble in ethyl acetate or acetone, very slightly soluble in benzene, almost insoluble in water or methanol.
specific rotation
take this product, precision weighing, plus anhydrous ethanol dissolution and quantitative dilution of about 20mg per lml solution, according to the law (General 0621), the specific rotation was 34 ° to 40 °.
Last Update:2022-01-01 11:42:04
Stanozolol CIII (200 mg) - Differential diagnosis
Authoritative Data Verified Data
- take about 2mg of this product, add 3ml of p-dimethylaminobenzaldehyde test solution, appear yellow-green, put the UV lamp (365nm) under the inspection, show yellow-green fluorescence.
- take this product, add anhydrous ethanol to dissolve and dilute to make a solution containing about 40ug per lml, and measure by UV-Vis spectrophotometry (General 0401), there is a maximum absorption at a wavelength of 224nm.
- The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 597).
Last Update:2022-01-01 11:42:04
Stanozolol CIII (200 mg) - Exam
Authoritative Data Verified Data
Related substances
take this product, add dichloromethane-anhydrous ethanol (9:1) dissolved and diluted to make a solution containing 10 mg per 1ml, as a solution for the test sample; Take appropriate amount of precision, the solutions containing l0ug, 30ug and 50ug in each lml were prepared by diluting with dichloromethane-anhydrous ethanol (9:1), respectively, as a series of control solutions; add dichloromethane-absolute ethanol (9:1) to the control of stanozolol and methanolide (impurity I). Dissolve and dilute to prepare a solution containing 10 mg of stanozolol and methylprednisolone per 1ml. 1 mg solution, as a control solution. According to the thin layer chromatography (General 0502) test, absorb 10 u1 of each of the above 5 solutions, respectively point on the same silica gel G thin layer plate, with chloroform-methanol (19:1) as the developing solvent, spread out, dry, spray with 20% sulfuric acid ethanol solution, heated at 100°C for 10~15 minutes until the spots are clear, and set the UV lamp (365nm) to view. The control solution should show two clearly separated spots. If the test solution shows impurity spots, compared with the main spots of the series of control solutions, the total amount of impurities shall not exceed 2.0%.
loss on drying
take this product, dry to constant weight at 105°C, weight loss shall not exceed 1.0% (General rule 0831).
ignition residue
not more than 0.1% (General rule 0841).
Last Update:2022-01-01 11:42:05
Stanozolol CIII (200 mg) - Content determination
Authoritative Data Verified Data
take this product dry product about 0.27g, precision weighing, add glacial acetic acid 30ml micro heat to dissolve, cool, add crystal violet indicator liquid 1 drop, with perchloric acid titration solution (0.1 mol /L) titration to the solution is green, and the result of the titration is corrected with a blank test. Each 1 ml of perchloric acid titration solution (0.1 mol /L) corresponds to 32.85mg of C21H32N2O.
Last Update:2022-01-01 11:42:06
Stanozolol CIII (200 mg) - Category
Authoritative Data Verified Data
Last Update:2022-01-01 11:42:06
Stanozolol CIII (200 mg) - Storage
Authoritative Data Verified Data
light shielding, closed storage.
Last Update:2022-01-01 11:42:06
Stanozolol CIII (200 mg) - Stanozolol tablets
Authoritative Data Verified Data
This product contains stanozolol (C21H32N20) should be 90% ~ 110.0% of the label amount.
trait
This product is white tablet.
identification
- take an appropriate amount of fine powder of this product (equivalent to 2mg of stanozolol), add 5ml of ethanol, heat to boiling in a water bath, filter, and evaporate the filtrate on the water bath, 3ml of p-dimethylaminobenzaldehyde solution was added to the residue, which showed yellow color. The residue was examined under a UV lamp (365nm) and showed yellow-green fluorescence.
- in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
examination
- Related substances take 25 tablets of this product, grind it, take appropriate amount (about 40mg equivalent to stanozolol), add 15ml of dichloromethane-anhydrous ethanol (9:1); shaking to dissolve stanozolol, rapidly filtering, blowing nitrogen at room temperature to dryness, and dissolving the residue with 3ml of the above solvent as a test solution; tested according to the method under stanozolol related substances. Test solution such as impurity spots, compared with the control solution of the main spot, not deeper, the total amount of impurities should not exceed 2.0%.
- Content uniformity take 1 tablet of this product, put it in a 25ml measuring flask, add 1ml of water, shake it to disintegrate, then add 20ml of anhydrous ethanol, sonicate and shake constantly to dissolve stanozolol, let it cool, dilute to scale with absolute ethanol, shake well, rapidly filter, and determine the content according to the method under the content determination item, except for the limit of ± 20%, the provisions (General 0941) shall be met.
- the dissolution of this product, according to the dissolution and release determination method (General rule 0931 third method), with hydrochloric acid solution (9-1000) 250ml as the dissolution medium, the rotation speed is 50 rpm, operate according to law, after 45 minutes, take the solution and filter, take the filtrate as the test solution; Take another 20mg of stanozolol reference, weigh it accurately, put it in 50ml measuring flask, add 15ml ethanol, heat in a warm water bath to dissolve, cool, add 1.Omol/L hydrochloric acid solution 5.0ml, diluted with water to the scale, shake well, take 2ml, put it in a 100ml measuring flask, dilute it to the scale with hydrochloric acid solution (9-1000), shake well, as a reference solution (in the new system). The sample solution and the reference solution are each 50 u1, and the dissolution amount of each tablet is calculated according to the method under the content determination item. The limit is 75% of the labeled amount and shall be in accordance with the provisions.
- others shall be in accordance with the relevant provisions under the item of tablets (General rule 0101).
Content determination
- measured by high performance liquid chromatography (General 0512).
- chromatographic conditions and system suitability test using eighteen alkyl silane bonded silica gel as filler; Methanol -0.05mol/L ammonium dihydrogen phosphate solution (75:25) as mobile phase; The detection wavelength was 224mn. The number of theoretical plates is not less than 3500 calculated from the peak of Stanozolol.
- determination of 20 tablets of this product, precision weighing, fine grinding, precision weighing an appropriate amount (about 2mg equivalent to stanozolol), put it in a 25ml measuring flask, add an appropriate amount of anhydrous ethanol, sonicate and shake constantly to dissolve stanozolol, let it cool, dilute to scale with absolute ethanol, shake well, rapidly filter, and take continued filtrate as test solution, A 10ul injection liquid chromatograph was accurately measured, and the chromatogram was recorded. Another reference substance of stanozolol was accurately weighed, dissolved and quantitatively diluted with anhydrous ethanol to make a solution containing about 80ug per lml, same method determination. According to the external standard method to calculate the peak area, that is.
category
isoxazole.
specification
2mg
storage
light shielding, closed storage.
Last Update:2022-01-01 11:42:07
Stanozolol CIII (200 mg) - Reference Information
pharmacological action | kanglilong is anabolic hormone. Its protein assimilation effect is strong, 30 times that of methyltestosterone, while androgen activity is only 1/4 of the latter. This product has the effects of promoting protein synthesis, inhibiting protein heterogenesis, reducing serum cholesterol and triglycerides, promoting calcium and phosphorus deposition and reducing bone marrow suppression. It can also increase physical strength, appetite and weight gain. |
Indications | Canolone is clinically used for severe illness and postoperative frail emaciation, the elderly and infirm, as well as various chronic wasting diseases, osteoporosis, pediatric dysplasia, aplastic anemia, leukopenia, thrombocytopenia, hyperlipidemia, etc. |
adverse reactions | lower limbs and facial edema may occur at the initial stage of taking medicine. Long-term application may lead to jaundice and liver function damage, which may lead to liver cancer. Some have delayed menstruation and female masculinization. |
use | for chronic wasting diseases, serious diseases and postoperative infirmity, old age and infirmity, osteoporosis, dysplasia in children, aplastic anemia, etc. Prevention and treatment of hereditary angioedema |
NIST chemical information | The information is: webbook.nist.gov provides (external link) |
toxic substance data | The information is: pubchem.ncbi.nlm.nih.gov Provide (external link) |
Last Update:2024-04-09 20:48:19